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(MSCDFSM) Nutritional Biochemistry (TMA-2) ANSWER 2017

b) What is oxidative phosphorylation? The oxidation of one molecule of NADH or FADH2 corresponds to the synthesis of how manyATPs?

ANS- Most of the usable energy obtained from the breakdown of carbohydrates or fats is derived by oxidative phosphorylation, which takes place within mitochondria. For example, the breakdown of glucose by glycolysis and the citric acid cycle yields a total of four molecules of ATP, ten molecules of NADH, and two molecules of FADH2 (see Chapter 2). Electrons from NADH and FADH2 are then transferred to molecular oxygen, coupled to the formation of an additional 32 to 34 ATP molecules by oxidative phosphorylation. Electron transport and oxidative phosphorylation are critical activities of protein complexes in the inner mitochondrial membrane, which ultimately serve as the major source of cellular energy.

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